(2) The "Introduction" section includes more detail about quality control applications. The main changes to the manuscript are listed below: (1) The abstract was changed to highlight the memory comparison between QC software tools, and no longer mentions that FastQC does not run on long-read samples. The code changes that relate to the core computations were not altered since version 0.1.0 (used in the previous version of the manuscript), and we have verified that the times reported in Table 3 remain the same in both versions. Falco version 0.2.4 was used ion this revised manuscript. The accompanying code for Falco has also undergone updates for this review. No other table or figured was altered from the first version of the manuscript. Tables 3 and 4 were expanded to include time measurements for FastQC on long-read samples. Changes to the text were made in all sections. This article has been updated to address reviewer responses.
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